International Journal of Chronic Obstructive Pulmonary Disease
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#1Alex D. Federman (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 37
#2Rachel O'Conor (NU: Northwestern University)H-Index: 17
Last. Juan P. Wisnivesky (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 60
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Introduction Medication adherence is often low among people with chronic obstructive pulmonary disease (COPD) and medication regimen complexity may be a contributing factor. In this study, we sought to examine the role of medication regimen complexity in COPD medication adherence among patients with multimorbidity. Methods We performed cross-sectional analysis of data on COPD patients in primary care and pulmonary practices in New York City and Chicago (n=400). Regimen complexity was represented...
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#1Chu-Yun Liu (Fujian Medical University)
#2Jianhua Wu (Fujian Medical University)H-Index: 1
Last. Xiaohua Gao (Fujian Medical University)H-Index: 1
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Objective To evaluate the effect of doxofylline on reducing the inflammatory response in mechanically ventilated rats with chronic obstructive pulmonary disease (COPD). Methods A total of 40 eight-week-old male Sprague Dawley rats were randomly divided into four groups of 10 rats each: a control group (group C), a model group (group M), a model + natural saline group (group N), and a doxofylline group (group D). Then mechanical ventilation, drug intervention, and the extraction of the experiment...
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#1Mandy Scheermesser (Zurich University of Applied Sciences/ZHAW)H-Index: 6
#2Leah Reicherzer (Zurich University of Applied Sciences/ZHAW)
Last. Anne-Kathrin Rausch Osthoff (Zurich University of Applied Sciences/ZHAW)H-Index: 4
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Objective null The aim of this study was to explore to what extent a combined counselling and pulmonary rehabilitation program (PR) influences the perception of physical activity (PA) and motivation for behavioral change in PA in individuals with COPD. The results of previous quantitative trial that investigated the effect of this combined treatment on daily PA were inconclusive. It is conjectured that a more targeted tailoring of the counselling and PR intervention could improve its effectivene...
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#1Yuanlong Hu (SDUTCM: Shandong University of Traditional Chinese Medicine)
#2Xiaomeng Cheng (SDUTCM: Shandong University of Traditional Chinese Medicine)
Last. Xianhai Chen (SDUTCM: Shandong University of Traditional Chinese Medicine)
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Purpose This study aimed to identify the COPD molecular subtypes reflecting pulmonary function damage on the basis of metabolism-related gene expression, which provided the opportunity to study the metabolic heterogeneity and the association of metabolic pathways with pulmonary function damage. Methods Univariate linear regression and the Boruta algorithm were used to select metabolism-related genes associated with forced expiratory volume in the first second (FEV1) and FEV1/forced vital capacit...
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#1D. Meza (NU: Northwestern University)
#2Basil Khuder (NU: Northwestern University)H-Index: 2
Last. Paul A. Reyfman (NU: Northwestern University)H-Index: 14
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#1Rachel PullenH-Index: 1
#2Marc MiravitllesH-Index: 85
Last. Shigeo Muro (Nara Medical University)H-Index: 33
view all 23 authors...
Acknowledgments We thank Dr Seyi Soremekun, Jonathan Marshall, Jennie Medin and Irena Brookes-Smith for their valuable contributions to the design of the study. We would also like to acknowledge Ms Andrea Teh Xin Yi (BSc, Hons) of the Observational and Pragmatic Research Institute (OPRI), Singapore, for editorial and formatting assistance which supported the development of this publication. Professor Dave Singh is supported by the National Institute for Health Research (NIHR) Manchester Biomedic...
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