Background: Recent developments in technologies have offered opportunities to measure the exposome with unprecedented accuracy and scale. However, because most investigations have targeted only a f...
Last. Hongqiao Zhang(SC: University of Southern California)H-Index: 26
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Background: Exposure to ambient air pollution particulate matter (PM) is associated with increased risk of dementia and accelerated cognitive loss. Vascular contributions to cognitive impairment ar...
Background: Chronic environmental exposure to manganese (Mn) can cause debilitating damage to the central nervous system. However, its potential toxic effects on the enteric nervous system (ENS) ha...
Last. Walter Vetter(University of Hohenheim)H-Index: 48
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Background: The current production and use of chlorinated paraffins (CPs) at >1 million tons/y likely exceeds the lifetime production of polychlorinated biphenyls (PCBs). These persistent organic p...
#2Carlos F. Aylwin(Oregon National Primate Research Center)H-Index: 5
Last. Ezio Tirelli(University of Liège)H-Index: 23
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BACKGROUND The effects of endocrine-disrupting chemicals (EDCs) on fertility and reproductive development represent a rising concern in modern societies. Although the neuroendocrine control of sexual maturation is a major target of EDCs, little is known about the potential role of the hypothalamus in puberty and ovulation disruption transmitted across generations. OBJECTIVES We hypothesized that developmental exposure to an environmentally relevant dose of EDC mixture could induce multi- and/or ...