International Journal of Clinical Oncology
Papers 3,109
1 page of 311 pages (3,109 results)
#1Lital Oz-AlcalayH-Index: 1
#2Sarah ElitzurH-Index: 12
Last. Oded GiladH-Index: 8
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#1Shuichiro KobayashiH-Index: 10
#2Masaya ItoH-Index: 7
Last. Fumitaka KogaH-Index: 34
view all 6 authors...
OBJECTIVE To develop preoperative models as a guide to indications for neoadjuvant chemotherapy (NAC) and regional lymph node dissection (LND) before and at radical nephroureterectomy (RNU), respectively, in patients with non-metastatic upper tract urothelial carcinoma (UTUC) by incorporating the systemic immune-inflammation index (SII). METHODS This retrospective study enrolled 103 consecutive patients with UTUC undergoing RNU. The SII was calculated as neutrophils × platelets / lymphocytes. Mu...
#1Tadashi KumamotoH-Index: 15
#2Fumito Yamazaki (Keio University)H-Index: 3
Last. Yukiko Tsunematsu (Saga Group)
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#1Toshihiro Nakao (Tokushima University)H-Index: 7
#2Mitsuo Shimada (Tokushima University)H-Index: 70
Last. Yosuke Iwakawa (Tokushima University)
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BACKGROUND The Immunoscore is a useful prognostic and predictive factor for colorectal cancer. Frailty predicts overall and recurrence-free survival following resection of colorectal cancer, and the immunosuppressive state of frailty might affect tumor progression. This study investigated the relationship between the Immunoscore and frailty in colorectal cancer. METHODS This retrospective study included patients who underwent radical surgery for stage II and III colorectal cancer (n = 108). Pati...
#1Eunji KimH-Index: 27
#2Tae Hyung Kim (Yonsei University)H-Index: 7
Last. Mi-Sook KimH-Index: 18
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This study evaluated the prognostic value of leukocyte, lymphocyte, and neutrophil counts in anal cancer patients undergoing concurrent chemoradiotherapy (CCRT). Multi-institutional retrospective data review included 148 non-metastatic anal cancer patients treated with definitive CCRT with 5-fluorouracil plus mitomycin C between the year 2001 and 2019. The median radiation dose to the primary tumor was 54 Gy with a median pelvic dose of 45 Gy. Median follow-up duration was 56 months, and complet...
#1Junshen He (SMU: Southern Medical University)H-Index: 1
#2Donglin LiH-Index: 2
Last. Chunlin Chen (SMU: Southern Medical University)H-Index: 10
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This study aimed to compare the 5-year overall survival (OS) and 5-year DFS disease-free survival (DFS) of abdominal radical hysterectomy (ARH) and radiochemotherapy (R-CT) for stage IIA2 (FIGO 2018) cervical cancer patients. Based on this multicenter, retrospective cohort study based on data from the clinical diagnosis and treatment of cervical cancer in China (Four C) database, 609 cases with 2018 FIGO stage IIA2 cervical cancer from 2004 to 2018 were reviewed. The 5-year OS and 5-year DFS of ...
#1Hiroaki Nozawa (UT: University of Tokyo)H-Index: 21
#2Kazushige Kawai (UT: University of Tokyo)H-Index: 30
Last. Soichiro Ishihara (UT: University of Tokyo)H-Index: 30
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Para-aortic lymph node (PALN) metastasis is an ominous manifestation indicating a poor prognosis in colorectal cancer (CRC) patients; however, some treatments prolong survival. In this study, we investigated predictors of prolonged survival in CRC patients after PALN metastasis. We examined 141 patients with CRC that metastasized to the PALNs from CRC with or without extra-PALN metastasis. Among clinicopathological parameters, factors associated with survival after PALN metastasis were identifie...
#2Kirill V. LepikH-Index: 5
Last. A. D. KulaginH-Index: 7
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Therapy of patients with relapsed and refractory classic Hodgkin lymphoma (r/r cHL) after PD-1 inhibitors failure remains an unresolved issue. The aim of this study was to evaluate the efficacy and safety of the combination of nivolumab with brentuximab vedotin (Nivo + BV) after nivolumab monotherapy failure. This study retrospectively analyzed 21 patients with r/r cHL who were treated with the combination of Nivo + BV after Nivo failure. The response was evaluated by PET–CT scan according to th...
Last. Joji Kitayama (Jichi Medical University)H-Index: 45
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Patients with peritoneal dissemination (PD) caused by abdominal malignancies are often associated with massive ascites, which shows extremely dismal prognosis because of the discontinuation of systemic chemotherapy mostly due to poor performance status. Many treatment methods, such as simple drainage, peritoneovenous shunting (PVS) and cell-free and concentrated reinfusion therapy (CART), have been used for symptom relief. However, the clinical efficacies of these methods have not been fully inv...
#1Satoshi TamadaH-Index: 15
#2Chihiro KondohH-Index: 8
Last. Hirotsugu Uemura (Kindai University)H-Index: 32
view all 17 authors...
In the phase III open-label KEYNOTE-426 (NCT02853331) study, first-line pembrolizumab and axitinib improved overall survival (OS) and progression-free survival (PFS) versus sunitinib for metastatic renal cell carcinoma (mRCC). KEYNOTE-426 evaluated patients enrolled from 25 sites in Japan. Patients enrolled in Japan were included in this post hoc subgroup analysis. Adults with clear cell mRCC were randomly assigned 1:1 to receive intravenous pembrolizumab 200 mg every 3 weeks plus oral axitinib ...
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