Papers 7271
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#1Shria Kumar (JHUSOM: Johns Hopkins University School of Medicine)
#2Monica SaumoyH-Index: 8
Last. Michael GogginsH-Index: 118
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Objectives null Data from the International Cancer of the Pancreas Screening Consortium studies have demonstrated that screening for pancreatic ductal adenocarcinoma can be effective and that surveillance improves survival in high-risk individuals. Endoscopic ultrasound (EUS) and cross-sectional imaging are both used, although there is some suggestion that EUS is superior. Demonstration of the cost-effectiveness of screening is important to implement screening in high-risk groups. null Methods n...
#1Luis F. Lara (The Ohio State University Wexner Medical Center)H-Index: 22
#2Laura NemerH-Index: 1
Last. Somashekar G. KrishnaH-Index: 21
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OBJECTIVES Cannabis legalization has increased its use. The incidence of acute pancreatitis (AP) and severe acute pancreatitis (SAP) has also increased. In this study, data on pancreatitis were obtained from 2 states before and after cannabis legalization and compared with 2 states without legalized cannabis. METHODS Data were extracted from State Inpatient Databases from the states of Colorado and Washington before recreational cannabis legalization (2011) and after legalization (2015). Arizona...
Objectives Exocrine pancreatic insufficiency is a frequent and clinically relevant complication of pancreatic cancer probably secondary to pancreatic duct obstruction. We aimed at evaluating the impact of endoscopic pancreatic drainage on pancreatic function in patients with unresectable pancreatic cancer. Methods A double-blind, prospective, randomized, single-center, interventional study was designed. Patients undergoing endoscopic retrograde cholangiopancreatography for jaundice secondary to ...
#1Grace M. Lee (Harvard University)H-Index: 67
#2Daniel KimH-Index: 91
Last. Jennifer Y. WoH-Index: 28
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OBJECTIVES We evaluated the outcomes of metastatic pancreatic cancer (MPC) patients who underwent liver metastases (LMs)-directed ablative radiotherapy (RT) and sought to characterize patients with more favorable prognosis. METHODS A retrospective analysis of 76 MPC patients who underwent ablative RT (median dose, 50 Gy) to LM at 3 academic centers between 2008 and 2018 was performed. Endpoints were local control (LC), progression-free survival, and overall survival (OS) since RT. RESULTS Median...
#1Masanori Kobayashi (Tokyo Medical and Dental University)H-Index: 1
#2Akashi FujitaH-Index: 4
Last. Shomei RyozawaH-Index: 18
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OBJECTIVES Early detection of pancreatic cancer is notoriously difficult. A novel cancer diagnostic method using the ability of nematodes to detect odor of urine samples has been developed (N-NOSE). This method has a high sensitivity and specificity for various cancers; however, it has not yet been verified in pancreatic cancer. We examined the usefulness of this method to aid early diagnosis of pancreatic cancer in a cancer center. METHODS We collected urine samples and clinical data from patie...
#1Marina Baretti (The Ohio State University Wexner Medical Center)H-Index: 3
#1Marina Baretti (The Ohio State University Wexner Medical Center)
Last. Ana De Jesus-AcostaH-Index: 14
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OBJECTIVES The aim of this study was to characterize the tumor microenvironment of patients with gastroenteropancreatic neuroendocrine tumors relative to progression-free survival (PFS). METHODS Immune profiling for CD3, CD8, programmed death-1/programmed death-ligand 1, and indoleamine 2,3-dioxygenase expression in 2 cohorts of gastroenteropancreatic neuroendocrine tumors: patients with short PFS (<4 years, n = 12) versus long PFS (≥4 years, n = 14) after surgery. Immune infiltrates in the tumo...
#1Stephen A. Firkins (The Ohio State University Wexner Medical Center)
#2Phil A. HartH-Index: 29
Last. Somashekar G. KrishnaH-Index: 21
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OBJECTIVES There is a paucity of studies evaluating predictors of new-onset diabetes mellitus (DM) after acute pancreatitis (AP-related DM). We used a population-based database to evaluate predictors of AP-related DM. METHODS The Nationwide Readmissions Database (2010-2014) was used to identify all nondiabetic adults with an index primary diagnosis of AP. Multiple exclusions were applied to identify cohorts with and without AP-related DM. A case-control study was conducted to identify risk facto...
Last. Ursula FalkmerH-Index: 19
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OBJECTIVES The aim of this study was to identify patterns of palliative chemotherapy (CTh) and the associated overall survival (OS) in patients with pancreatic cancer, with specific focus on age. METHODS Between May 1, 2011, and April 30, 2016, 4260 patients were registered in the Danish Pancreatic Cancer Database. The 1715 patients receiving palliative CTh were retrieved. Age was grouped into less than 70, 70 to less than 75 and 75 years or more. RESULTS Of the 1715 patients receiving first-lin...
#1Shozo Mori (Dokkyo Medical University)H-Index: 6
#2Taku AokiH-Index: 38
Last. Keiichi KubotaH-Index: 60
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OBJECTIVES Although neoadjuvant chemotherapy (NAC)-gemcitabine plus S-1 (GS) has been reported to have a survival benefit in patients with resectable pancreatic ductal adenocarcinoma (PDAC), optimal candidates for NAC-GS have not been clearly identified. METHODS A total of 81 patients with PDAC who underwent pancreatectomy after NAC-GS between 2013 and 2019 were divided into 2 groups based on Evans classification: grade I ( 10% tumor cell destruction, n = 62). Univariate and multivariate analyse...
#1Alexandria J. Robbins (UMN: University of Minnesota)H-Index: 3
#2Elizabeth R LusczekH-Index: 15
Last. Gregory J BeilmanH-Index: 47
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OBJECTIVES This study aimed to quantify the prevalence of venous thromboembolic (VTE) events in patients with pancreatitis requiring hospitalization and its impact on outcomes. METHODS Adult patients admitted from 2011 to 2018 for pancreatitis were identified. Every admission for pancreatitis in the first year after diagnosis was evaluated for a VTE (pulmonary embolism, deep vein thrombosis, or mesenteric vessel thrombosis) within 30 days of discharge. Characteristics of patients who developed a...
Top fields of study
Pancreatic cancer
Diabetes mellitus