Giuseppe Mancia
University of Milano-Bicocca
Internal medicineEndocrinologySurgeryAmbulatory blood pressureCardiologyIntensive care medicineHemodynamicsBaroreflexLeft ventricular hypertrophyEssential hypertensionHeart rateHeart failurePopulationAmbulatoryAnesthesiaDiabetes mellitusDiastoleMedicineBaroreceptorBlood pressure
Publications 1542
#1Fosca Quarti-Trevano (University of Milano-Bicocca)H-Index: 24
#2Annalisa Biffi (University of Milano-Bicocca)H-Index: 5
Last. Guido Grassi (University of Milano-Bicocca)H-Index: 100
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BACKGROUND Neuroadrenergic overdrive occurs in obstructive sleep apnea syndrome (OSAS). However, the small sample size of the microneurographic studies, heterogeneity of the patients examined, presence of comorbidities, represented major weaknesses not allowing to precisely define the main features of the phenomenon, particularly in nonobese patients. OBJECTIVE This meta-analysis evaluated 850 participants recruited in 26 microneurographic studies, based on muscle sympathetic nerve activity (MSN...
#1Claudio Borghi (UNIBO: University of Bologna)H-Index: 42
#2Giuseppe Ambrosio (University of Perugia)H-Index: 68
Last. Giuseppe Mancia (University of Milano-Bicocca)H-Index: 166
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Current hypertension guidelines suggest various strategies to reduce blood pressure levels, thereby reducing cardiovascular events: combinations of drugs with different mechanisms of action, such as an angiotensin converting enzyme inhibitors (ACEIs) and a diuretic, are the cornerstone of the modern treatment of hypertension, also as initial therapy. Among ACEIs, zofenopril has been shown to be effective in the management of hypertension both as monotherapy and in combination with a diuretic: zo...
#1Kazem RahimiH-Index: 59
#2Zeinab BidelH-Index: 8
Last. Larry AgodoaH-Index: 1
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Summary null Background null The effects of pharmacological blood-pressure-lowering on cardiovascular outcomes in individuals aged 70 years and older, particularly when blood pressure is not substantially increased, is uncertain. We compared the effects of blood-pressure-lowering treatment on the risk of major cardiovascular events in groups of patients stratified by age and blood pressure at baseline. null Methods null We did a meta-analysis using individual participant-level data from randomis...
2 CitationsSource
#1Federico Rea (University of Milano-Bicocca)H-Index: 50
#2Laura Savaré (University of Milano-Bicocca)
Last. Giuseppe Mancia (University of Milano-Bicocca)H-Index: 166
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INTRODUCTION Although several studies have shown that a simplified cardiovascular drug treatment leads to better treatment adherence, limited and conflicting findings have been reported on the separate or single-pill combination of the now recommended association between a statin and ezetimibe. We addressed this issue in a large cohort of patients newly treated with statins to whom ezetimibe was additionally administered, either separately or as a single-pill combination. METHODS A total of 256,...
1 CitationsSource
#1Giuseppe Mancia (University of Milano-Bicocca)H-Index: 166
#1Johanne Tremblay (UdeM: Université de Montréal)H-Index: 64
#2Mounsif Haloui (UdeM: Université de Montréal)H-Index: 6
Last. Lara Santucci (UdeM: Université de Montréal)H-Index: 1
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#1Cesare Cuspidi (University of Milano-Bicocca)H-Index: 62
#2Marijana TadicH-Index: 24
Last. Guido GrassiH-Index: 100
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AIM Available evidence on the association between reverse dipping pattern and subclinical cardiac damage is scanty. We performed a systematic meta-analysis of echocardiographic studies in order to provide an updated and comprehensive information on this issue. METHODS The PubMed, OVID-MEDLINE, and Cochrane library databases were analyzed to search English-language articles published from January from the inception up to 31 July 2020. Studies were identified by using MeSH terms and crossing the f...
1 CitationsSource
#1Michael Böhm (Saarland University)H-Index: 99
#2Helmut SchumacherH-Index: 31
Last. Johannes F.E. MannH-Index: 63
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#1Alexandros Kasiakogias (UoA: National and Kapodistrian University of Athens)H-Index: 15
#2Enrico Agabiti Rosei (University of Brescia)H-Index: 59
Last. Athanasios J. ManolisH-Index: 49
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Hypertension constitutes a major risk factor for heart failure with preserved ejection fraction (HFpEF). HFpEF is a prevalent clinical syndrome with increased cardiovascular morbidity and mortality. Specific guideline-directed medical therapy (GDMT) for HFpEF is not established due to lack of positive outcome data from randomized controlled trials (RCTs) and limitations of available studies. Although available evidence is limited, control of blood pressure (BP) is widely regarded as central to t...