Notch, apoptosis and cancer
Abstract
Proper embryonic development and normal tissue homeostasis require a series of molecular processes, regulating cell growth, differentiation and apoptosis. Perturbation in any of these processes invariably contributes to the development of cancer. In particular, defects in apoptosis are seen in virtually all types of human cancers. The Notch pathway plays an important role in cell fate determination in both embryonic development and organ...
Paper Details
Title
Notch, apoptosis and cancer
Published Date
Jan 1, 2012
Volume
727
Pages
199 - 209
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