Optimization of spray drying process for formulation of solid dispersion containing polypeptide-k powder through quality by design approach

Volume: 284, Pages: 1 - 11
Published: Nov 1, 2015
Abstract
Polypeptide-k is an antidiabetic phytochemical isolated from dried and ripened seeds of Momordica charantia. The peptide has not been able to find much clinical use despite its established therapeutic effect. This is mainly attributed to its poor aqueous solubility. Present study presents the formulation of solid dispersion containing polypeptide-k to enhance its aqueous solubility. The study was carried out by employing the optimization...
Paper Details
Title
Optimization of spray drying process for formulation of solid dispersion containing polypeptide-k powder through quality by design approach
Published Date
Nov 1, 2015
Volume
284
Pages
1 - 11
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