Adipocyte activation of cancer stem cell signaling in breast cancer
Abstract
Signaling within the tumor microenvironment has a critical role in cancer initiation and progression. Adipocytes, one of the major components of the breast microenvironment, have been shown to provide pro-tumorigenic signals that promote cancer cell proliferation and invasiveness in vitro and tumorigenicity in vivo. Adipocyte secreted factors such as leptin and interleukin-6 (IL-6) have a paracrine effect on breast cancer cells. In...
Paper Details
Title
Adipocyte activation of cancer stem cell signaling in breast cancer
Published Date
Jan 1, 2015
Volume
6
Issue
2
Pages
39 - 39
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