Volume: 16, Issue: 4, Pages: 156 - 165
Published: Dec 1, 2007
Abstract
Tissue repair begins with clot formation and platelet degranulation, which release the growth factors (GFs) necessary for wound repair. Platelet-derived GFs are biologically active substances that enhance tissue repair mechanisms such as chemotaxis, cell proliferation, angiogenesis, extracellular matrix deposition, and remodeling. This review describes the biological background of the topical therapy of wounds and soft-tissue injuries with...
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