Reliability of a new modified tear breakup time method: dry tear breakup time

Published on Jun 20, 2015in Graefes Archive for Clinical and Experimental Ophthalmology3.117
· DOI :10.1007/S00417-015-3080-5
Kyung Tae Kim4
Estimated H-index: 4
(CBNU: Chungbuk National University),
Jae-hyung Kim3
Estimated H-index: 3
(CBNU: Chungbuk National University)
+ 2 AuthorsSungmin Hyung4
Estimated H-index: 4
(CBNU: Chungbuk National University)
Background Tear breakup time (TBUT) is a useful technique for diagnosing dry eye disease (DED). The conventional method of measuring TBUT using fluorescein strips adds supplemental normal saline (NS) to the tear film (wet tear breakup time, WBUT) but does not represent the actual state of the tear film. We introduced a new TBUT method—dry tear breakup time (DBUT)—and investigated its reliability.
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lies on the misunderstanding of the expression 'replace' in the abstract of the article. Our intention in this study was not to replace the WBUT method completely with the DBUT method for diagnosing dry eye disease, because an AUROC curve of WBUT was less than that of DBUT. Instead, the intention in this study was to intro- duce a new modified diagnostic method. However, we do agree with Dr. Sabour claims that further investiga- tion of other estimates for validity is needed.
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