Internal medicine

Business

Disease

Conservative management

Coronary disease

Conservative treatment

Ischemia

Cardiology

Surgery

Intensive care medicine

Business administration

Management strategy

Coronary heart disease

Medicine

Circulation

The ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) compared an initial invasive versus an initial conservative management strategy for patients with chronic coronary disease and moderate or severe ischemia, with no major difference in most outcomes during a median of 3.2 years. Extended follow-up for mortality is ongoing.

Survival After Invasive or Conservative Management of Stable Coronary Disease