Electrical engineering

Internal medicine

Viral shedding

Virus

Disease

Proctitis

Biology

Gene

Outbreak

Engineering

Virology

Monkeypox

Men who have sex with men

Syphilis

Vaccinia

Recombinant DNA

Ulcerative colitis

Human immunodeficiency virus (HIV)

Biochemistry

Medicine

Transmission (telecommunications)

Open Forum Infectious Diseases

We describe the first 25 persons with HIV diagnosed with human monkeypox virus (MPXV) in our hospital in an ongoing outbreak in Spain. Proctitis was the predominant finding in 52%, and MPXV DNA was detected in rectal swabs from 90%. Proctitis and demonstration of MPXV in rectal swabs support the sexual transmission of MPXV.

Human Monkeypox in People With HIV: Transmission, Clinical Features, and Outcome