Internal medicine

Pancreas

Diabetes mellitus

Endocrinology

Initialization

Programming language

Type 2 diabetes

Insulin

Artificial pancreas

Meal

Insulin delivery

Computer science

Type 1 diabetes

Medicine

New England Journal of Medicine

Currently available semiautomated insulin-delivery systems require individualized insulin regimens for the initialization of therapy and meal doses based on carbohydrate counting for routine operation. In contrast, the bionic pancreas is initialized only on the basis of body weight, makes all dose decisions and delivers insulin autonomously, and uses meal announcements without carbohydrate counting.

Multicenter, Randomized Trial of a Bionic Pancreas in Type 1 Diabetes