Synthesis of 1, 3, 5-Trisubstituted Pyrazoline Nucleus Containing Compounds and Screening for Anti-Inflammatory Activity
Abstract
In this study, a novel series of heterocyclic compounds containing pyrazoline nucleus has been synthesized. The compounds were synthesized in two steps. Chalcone was synthesized in the first step by Claisen-Schmidt reaction, using 1-acetylnaphthalene and p-nitrobenzaldehyde as reactants. In the second step, the chalcone was cyclized in an acidic medium with some hydrazine derivatives to form pyrazolines. All the compounds were characterized by...
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Paper Details
Title
Synthesis of 1, 3, 5-Trisubstituted Pyrazoline Nucleus Containing Compounds and Screening for Anti-Inflammatory Activity
DOI
Published Date
Apr 9, 2022
Journal
Pages
151 - 154
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