Estimation and Validation of Remogliflozin Etabonate in Dosage form and in Bulk Drug by Spectrophotometeric Method

Published on Apr 9, 2022in International research journal of pharmacy0
· DOI :10.52711/0974-4150.2022.00028
Husnain Fathima0 (Department of Pharmaceutical Chemistry, MMU College of Pharmacy), Nirmal. T. Havannavar0 (Department of Pharmaceutical Chemistry, MMU College of Pharmacy), Afnaz Jahan0 (Department of Pharmaceutical Chemistry, MMU College of Pharmacy)
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Abstract
A simple, sensitive, accurate, rapid and economical Spectrophotometric method was developed for estimation and validation of Remogliflozin Etabonate in pure drug and tablet dosage form. The absorbance was measured at 239.8nm using Ethanol as solvent system. It obeyed Beer’s law at the concentration range of 2-14µg/ml with coefficient of correlation (r2) of 0.997. Limit of detection (LOD) was found to be 1.220µg/ml and Limit of quantitation (LOQ) was found to be 5.220µg/ml. The proposed analytical method was validated according to ICH guidelines, yielded good results concerning range, linearity, precision, accuracy, robustness and ruggedness.
References15
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