Pancreas transplantation

Transplantation

Kidney transplantation

Cohort study

Endocrinology

Insulin

Type 2 diabetes

Islet

Cohort

Internal medicine

Type 1 diabetes

Diabetes mellitus

Surgery

Medicine

The Lancet Diabetes & Endocrinology

We present the largest single-centre cohort study of long-term outcomes following islet transplantation. Although some limitations with our study remain, such as the retrospective component, a relatively small sample size, and the absence of non-transplant controls, we found that the combined use of anakinra plus etanercept and the BETA-2 score were associated with improved outcomes, and therefore these factors could inform clinical practice.

Pancreatic islet transplantation in type 1 diabetes: 20-year experience from a single-centre cohort in Canada