Globodera pallida, a non-transgenic invertebrate as a new model for investigating Alzheimer’s disease (and other proteinopathies)?

Biological models of Alzheimer’s disease (AD): Non-human models have contributed tremendously to the understanding of AD and its underlying pathological processes. These models have aided the investigation of the genetic and environmental risk factors. They also have enabled the progression of candidate therapies into human clinical trials. Because of similarities with human brain anatomy and genetics, rodent models have been used extensively to...