Internal medicine

Disease

Coronavirus disease 2019 (COVID-19)

Infectious disease (medical specialty)

Case-control study

Nested case-control study

Vaccination

Prospective cohort study

Immunology

Medicine

The Lancet Infectious Diseases

COVID-19 vaccines show excellent efficacy in clinical trials and effectiveness in real-world data, but some people still become infected with SARS-CoV-2 after vaccination. This study aimed to identify risk factors for post-vaccination SARS-CoV-2 infection and describe the characteristics of post-vaccination illness.

Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study