Aerospace engineering

Signaling proteins

Intersection (aeronautics)

Biology

Engineering

Lipid metabolism

Metabolism

Signal transduction

Computational biology

Cell biology

Cellular metabolism

Biochemistry

Molecular Cell

In this review, Liang et al. describe the recent development on the pivotal role of lipid metabolism, as well as various signaling pathways that modulate lipid metabolism, in ferroptosis. They also highlight some unanswered questions in the field and suggest potential ferroptosis induction-based cancer therapeutic strategies.

Ferroptosis at the intersection of lipid metabolism and cellular signaling