Bacteriophage

Escherichia coli

Biology

Gene

Intensive care medicine

Virology

Phage therapy

MEDLINE

Computational biology

Genetics

Biochemistry

Medicine

Antimicrobial Agents and Chemotherapy

Increasing antimicrobial resistance and medical device-related infections have led to a renewed interest in phage therapy as an alternative or adjunct to conventional antimicrobials. Expanded access and compassionate use cases have risen exponentially but have varied widely in approach, methodology, clinical situations in which phage therapy might be considered, dosing, route of administration, and outcomes.

Considerations for the Use of Phage Therapy in Clinical Practice