Pipeline (software)

Antibiotics

Bacteria

Escherichia coli

Biology

Microbiology

Gene

Gram

Intensive care medicine

Gram-negative bacteria

Programming language

Computer science

Genetics

Medicine

Antimicrobial Agents and Chemotherapy

The World Health Organization (WHO) has warned that our current arsenal of antibiotics is not innovative enough to face impending infectious diseases, especially those caused by multidrug-resistant Gram-negative pathogens. Although the current preclinical pipeline is well stocked with novel candidates, the last U.S.

Leaks in the Pipeline: a Failure Analysis of Gram-Negative Antibiotic Development from 2010 to 2020