Localized surface plasmon

Surface plasmon resonance

Plasmon

Optics

Physics

Cancer

Figure of merit

Surface plasmon

Cell

Nanoparticle

Biosensor

Nanotechnology

Chemistry

Materials science

HeLa

Cancer detection

Refractive index

Optoelectronics

Genetics

Biochemistry

Prism

Biology

Cancer cell

Applied Optics

This theoretical investigation proposes the preliminary stage detection of cancer cells using a prism-based surface plasmon resonance biosensor. The surface plasmon resonance (SPR) biosensor is label-free and rapid; it supports real-time investigations, including greater sensitivity, and it has an enormous possibility for detecting different forms of cancer. The refractive index alteration of cancer cells is 1.360-1.401. The performance of the SPR sensor has been analyzed. The different types of cancer cells for skin, cervical, blood, adrenal, and breast (type I and II) have been analyzed, and sensitivities of 292, 384, 229, 242, 254, and 261 (degree/RIU) have been achieved, respectively. A high figure of merit of 115.2RIU-1 has been achieved for HeLa cells and achieved detection accuracy of 0.32deg-1 for basal cells.

Surface plasmon biosensor based on Bi<sub>2</sub>Te<sub>3</sub> antimonene heterostructure for the detection of cancer cells

Surface plasmon biosensor based on Bi2Te3 antimonene heterostructure for the detection of cancer cells

Surface plasmon biosensor based on Bi₂Te₃ antimonene heterostructure for the detection of cancer cells