Internal medicine

Pathology

Adverse effect

Clinical endpoint

Placebo

Insulin pump

Diabetes mellitus

Crossover study

Endocrinology

Randomized controlled trial

Alternative medicine

Type 2 diabetes

Type 1 diabetes

Medicine

The Lancet Healthy Longevity

Hybrid closed-loop insulin delivery is safe and achieves superior glycaemic control to SAP therapy in older adults with long duration of type 1 diabetes. Importantly this was achieved without increasing the risk of hypoglycaemia in this population with risk factors for severe hypoglycaemia. This suggests that hybrid closed-loop therapy is a clinically important treatment option for older adults with type 1 diabetes.

Hybrid closed-loop glucose control compared with sensor augmented pump therapy in older adults with type 1 diabetes: an open-label multicentre, multinational, randomised, crossover study