Genetically modified mouse

Inflammation

Alzheimer's disease

Amyloid precursor protein

Neuroinflammation

Neuroscience

Disease

Biology

Gene

Cell biology

Amyloid (mycology)

Transgene

Phenotype

Pathology

Presenilin

Immunology

Genetics

Medicine

Frontiers in Neuroscience

Since 1995, more than 100 transgenic (Tg) mouse models of Alzheimer's disease (AD) have been generated in which mutant amyloid precursor protein (APP) or APP/presenilin 1 (PS1) cDNA is overexpressed (

Recent Advances in the Modeling of Alzheimer’s Disease