Cancer

Internal medicine

Etiology

Surgery

Pathology

Dermatology

Cervical lymph nodes

Metastasis

Disease

Fever of unknown origin

Cervical lymphadenopathy

Lymph

Differential diagnosis

Lymph node

Coronavirus disease 2019 (COVID-19)

Infectious disease (medical specialty)

Medicine

Cureus

Kikuchi-Fujimoto Disease (KFD) is a rare self-limiting condition of unknown etiology. It is characterized by fever, and lymphadenopathy most commonly involving posterior cervical lymph nodes. Although it is of uncertain etiology, it is associated with viral infections and autoimmune diseases. Distinction from lymphadenopathy-associated alternate disorders is crucial to avoid unneeded diagnostic procedures and treatment. KFD is diagnosed based on histopathologic examination of the excised lymph node. The management is supportive with favorable outcomes within a few weeks or months. In this case, we describe a 13-year-old boy who complained of painful cervical lymphadenopathy and fever for more than three weeks following COVID-19. Diagnostic workup has been established and KFD diagnosis made based on the histopathologic features of the involved lymph node. The patient showed complete recovery with no recurrence during follow-up. So, this case highlights the possible association between COVID-19 and KFD during this pandemic and keeping it in the differential diagnosis.

Kikuchi-Fujimoto Disease Following COVID-19