Physics

Computer graphics (images)

Artificial intelligence

Composite material

Materials science

Acoustics

Tandem

Identity (music)

Visualization

Computer science

Interactive visualization

Bioinformatics

Summary The visualization and analysis of genomic repeats is typically accomplished using dot plots; however, the emergence of telomere-to-telomere assemblies with multi-megabase repeats requires new visualization strategies. Here, we introduce StainedGlass, which can generate publication-quality figures and interactive visualizations that depict the identity and orientation of multi-megabase tandem repeat structures at a genome-wide scale. The tool can rapidly reveal higher-order structures and improve the inference of evolutionary history for some of the most complex regions of genomes. Availability and implementation StainedGlass is implemented using Snakemake and available open source under the MIT license at https://mrvollger.github.io/StainedGlass/. Supplementary information Supplementary data are available at Bioinformatics online.

StainedGlass: interactive visualization of massive tandem repeat structures with identity heatmaps