Principles and procedures for blood cultures : approved guideline

Published on Jan 1, 2007
Clinical1
Estimated H-index: 1
,
Michael L. Wilson1
Estimated H-index: 1
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#1Ibironke W. Apata (Emory University)H-Index: 2
#2Sarah Kabbani (CDC: Centers for Disease Control and Prevention)H-Index: 6
Last. Priti R. Patel (CDC: Centers for Disease Control and Prevention)H-Index: 28
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Antibiotic use is necessary in the outpatient hemodialysis setting because patients receiving hemodialysis are at increased risk for infections and sepsis. However, inappropriate antibiotic use can lead to adverse drug events, including adverse drug reactions and infections with Clostridioides difficile and antibiotic-resistant bacteria. Optimizing antibiotic use can decrease adverse events and improve infection cure rates and patient outcomes. The American Society of Nephrology and the US Cente...
1 CitationsSource
#1Mary Adamik (BioMérieux)
#2Anne Hutchins (BioMérieux)
Last. Parampal Deol (BioMérieux)H-Index: 7
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Delayed entry of patient blood culture samples into a microbial detection system is unavoidable at times, due to off-shift staffing or transporting samples to centralized laboratories. Pre-incubation time and temperature of blood culture bottles are the most critical factors impacting recovery and detection of microorganisms. A total of 1377 BACT/ALERT® (BTA) Fastidious Antimicrobial Neutralization (FAN® PLUS) bottles (FA PLUS, FN PLUS, and PF PLUS) were tested after delayed entry times of 24 an...
1 CitationsSource
#1Eric M. Ransom (WashU: Washington University in St. Louis)H-Index: 2
#2Zahra Alipour (WashU: Washington University in St. Louis)H-Index: 3
Last. Carey-Ann D. BurnhamH-Index: 18
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Timely diagnosis of microorganisms in blood cultures is necessary to optimize therapy. Although blood culture media and systems have evolved for decades, the standard interval for incubation prior to discard as negative has remained five days. Here, we evaluated the optimal incubation time for the BACT/ALERT VIRTUO blood culture detection system (bioMerieux) using FA Plus (aerobic) and FN Plus (anaerobic) resin culture bottles in routine clinical use. Following IRB approval, a retrospective revi...
2 CitationsSource
#1Ira M. Lubin (CDC: Centers for Disease Control and Prevention)H-Index: 17
#2J. Rex Astles (CDC: Centers for Disease Control and Prevention)H-Index: 9
Last. Matthew L Rubinstein (RU: Rutgers University)H-Index: 3
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Objectives Clinical laboratory testing provides essential data for making medical diagnoses. Generating accurate and timely test results clearly communicated to the treating clinician, and ultimately the patient, is a critical component that supports diagnostic excellence. On the other hand, failure to achieve this can lead to diagnostic errors that manifest in missed, delayed and wrong diagnoses. Content Innovations that support diagnostic excellence address: 1) test utilization, 2) leveraging ...
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Blood culture tests have a major role in rapid and accurate diagnosis and selection of optimal antibiotic treatment for infectious diseases. The true-positive and contamination rates of blood cultures are performance indicators for the practice of blood culture. However, the optimal number of blood cultures has not been adequately elucidated. We aimed to assess the validity of the number of blood cultures obtained in the hospital. We conducted a retrospective study of blood cultures collected fr...
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#1Stacey A. Maskarinec (Duke University)H-Index: 17
#2Lawrence P. Park (Duke University)H-Index: 32
Last. Joshua T. Thaden (Duke University)H-Index: 19
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Abstract Objectives The role of follow-up blood cultures (FUBCs) in management of gram-negative bacteremia (GNB) is poorly understood. This study aims to determine utility of FUBCs in identifying patients with increased mortality risk. Methods An observational study with a prospectively enrolled cohort of adult inpatients with GNB was conducted at Duke University Health System from 2002-2015. FUBCs were defined as blood cultures drawn from 24 hours to 7 days from initial positive blood culture. ...
10 CitationsSource
PURPOSE: We analyzed the workflow of the blood culture procedure with one blood culture incubator in the microbiology laboratory, in comparison with the workflow with the incubators systems placing outside, and in a microbiology laboratory without 24-h staffing. METHODS: We assessed the elapsed time (ET) and time-to-result (TTR) in the two laboratory workflows during 1 month period in consecutive years. First period with one BACT/ALERT 3D module located in the microbiology laboratory (ML) (acces...
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#1Diane C. Halstead (University of Texas MD Anderson Cancer Center)H-Index: 2
#2Robert L. SautterH-Index: 12
Last. Irving Nachamkin (HUP: Hospital of the University of Pennsylvania)H-Index: 60
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INTRODUCTION: Blood cultures (BCs) frequently become contaminated during the pre-analytic phase of collection leading to downstream ramifications. We present a summary of performance improvement (PI) interventions provided by four hospital systems and common factors that contributed to decreased blood culture contamination (BCC) rates. METHODS: Each hospital independently formed a multidisciplinary team and action plan for implementation of their intervention, focusing on the use of educational ...
3 CitationsSource
#1Tang-Her Jaing (CGU: Chang Gung University)H-Index: 22
#2Chih-Chen Chang (Memorial Hospital of South Bend)
Last. Pei-Kwei Tsay (CGU: Chang Gung University)H-Index: 26
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In this analysis, the levels of CRP and IL-8 were employed as a guide for designing the duration of antibiotics administration in the condition of febrile neutropenia. The importance of laboratory biomarkers is in the early diagnosis of critical illness and adjustment of further management. IL-8 is a useful biomarker for the early identification of critically ill patients, compared to CRP in FN.
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