Pregnancy and brain architecture: Associations with hormones, cognition and affect

Sex hormones such as estradiol (E2) have long‐lasting influence on brain architecture. Recent studies indicate further structural changes during hormonal transition periods including pregnancy, when women experience the greatest increase in sex hormone levels across their life span. In the present study, three groups of women ( n = 44) with different levels of E2 underwent structural magnetic resonance imaging: (1) first‐time pregnant women ( n...