Polygenic risk scores across the extended psychosis spectrum
Abstract
As early detection of symptoms in the subclinical to clinical psychosis spectrum may improve health outcomes, knowing the probabilistic susceptibility of developing a disorder could guide mitigation measures and clinical intervention. In this context, polygenic risk scores (PRSs) quantifying the additive effects of multiple common genetic variants hold the potential to predict complex diseases and index severity gradients. PRSs for schizophrenia...
Paper Details
Title
Polygenic risk scores across the extended psychosis spectrum
Published Date
Nov 26, 2021
Journal
Volume
11
Issue
1
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