Cyclical fate restriction: a new view of neural crest cell fate specification

Volume: 148, Issue: 22
Published: Nov 15, 2021
Abstract
Neural crest cells are crucial in development, not least because of their remarkable multipotency. Early findings stimulated two hypotheses for how fate specification and commitment from fully multipotent neural crest cells might occur, progressive fate restriction (PFR) and direct fate restriction, differing in whether partially restricted intermediates were involved. Initially hotly debated, they remain unreconciled, although PFR has become...
Paper Details
Title
Cyclical fate restriction: a new view of neural crest cell fate specification
Published Date
Nov 15, 2021
Volume
148
Issue
22
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