The price of certainty: when is a new therapy good enough?

“Our aim as scientists is objective truth; more truth, more interesting truth, more intelligible truth. We cannot reasonably aim at certainty.” Karl Popper (from In Search of a Better World , 1995). The enormous success of endovascular thrombectomy (EVT) for stroke treatment has engendered increasing interest from the medical scientific community as well as industry. New companies have been founded and substantial capital raised and used for...