Cationic Glycopolyelectrolytes for RNA Interference in Tick Cells

Volume: 23, Issue: 1, Pages: 34 - 46
Published: Nov 18, 2021
Abstract
The black-legged tick (Ixodes scapularis) is the primary vector for bacteria that cause Lyme disease (Borrelia burgdorferi), where numerous glycosylated tick proteins are involved at the interface of vector-host-pathogen interactions. Reducing the expression of key tick proteins, such as selenoprotein K (SelK), through RNA interference is a promising approach to reduce pathogen transmission, but efficient delivery of nucleic acids to arthropods...
Paper Details
Title
Cationic Glycopolyelectrolytes for RNA Interference in Tick Cells
Published Date
Nov 18, 2021
Volume
23
Issue
1
Pages
34 - 46
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