Effectiveness and safety of intravenous valproate in agitation: a systematic review

The use of intravenous valproate is not approved for clinical practice in psychiatry. Literature data pointed out for a potential usefulness of this route of administration for valproate, but there is no actual consensus.The aim of the present systematic review is to assess the effectiveness of intravenous valproate in agitation as well as general safety.A systematic review of studies evaluating the use of intravenous valproate in agitation was...