Obesity‐related genetic polymorphisms are associated with the risk of early puberty in Han Chinese girls

To explore the association between obesity and precocious puberty from the perspective of genetic polymorphism.Two hundred and ninety-eight pairs of girls in early puberty and age-matched controls (±3 months) were recruited. The genotypes of four obesity-related single-nucleotide polymorphism (SNP) loci (rs10968576, rs12935153, rs4674340 and rs7635103) were determined and the effect of variation on early puberty in Chinese Han girls was...