Axonal excitability changes in children with spinal muscular atrophy treated with nusinersen

Published: Nov 15, 2021
Abstract
Spinal muscular atrophy (SMA) is associated with developmental disruption of motor axons in ventral roots of the spinal cord alongside motor axon degeneration. The pathogenesis of peripheral axonal change during development is pertinent to understand treatment response. Nerve excitability techniques, stimulating the median motor nerve at the wrist, were utilised to investigate axonal change during neurodevelopment in 24 children with SMA,...
Paper Details
Title
Axonal excitability changes in children with spinal muscular atrophy treated with nusinersen
Published Date
Nov 15, 2021
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