756 Identifying the role of B7-H4 as a suppressor of tumor infiltrating lymphocytes and a target for immunotherapy in breast cancer

Volume: 9, Issue: Suppl 2, Pages: A791 - A791
Published: Nov 1, 2021
Abstract
Background Immune checkpoint inhibitors (ICI) have improved patient survival in some cancer types but yielded limited success in breast cancer. Combinations of ICI (αPD-L1/PD-1) and chemotherapy have been FDA-approved for metastatic TNBC patients, and potentially in the early breast cancer setting, but many patients remain non-responsive to ICI. B7-H4 is a B7 family ligand with proposed immunosuppressive functions being explored as a cancer...
Paper Details
Title
756 Identifying the role of B7-H4 as a suppressor of tumor infiltrating lymphocytes and a target for immunotherapy in breast cancer
Published Date
Nov 1, 2021
Volume
9
Issue
Suppl 2
Pages
A791 - A791
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