Mouse Digit Tip Regeneration Is Mechanical Load Dependent

Volume: 37, Issue: 2, Pages: 312 - 322
Published: Dec 7, 2021
Abstract
Amputation of the mouse digit tip results in blastema-mediated regeneration. In this model, new bone regenerates de novo to lengthen the amputated stump bone, resulting in a functional replacement of the terminal phalangeal element along with associated non-skeletal tissues. Physiological examples of bone repair, such as distraction osteogenesis and fracture repair, are well known to require mechanical loading. However, the role of mechanical...
Paper Details
Title
Mouse Digit Tip Regeneration Is Mechanical Load Dependent
Published Date
Dec 7, 2021
Volume
37
Issue
2
Pages
312 - 322
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