End stage renal disease has an early and continuous detrimental effect on regulatory T cells

Volume: 27, Issue: 3, Pages: 281 - 287
Published: Nov 15, 2021
Abstract
End stage renal disease (ESRD) is followed by disturbed adaptive immunity, together with alterations in T cell subsets, including CD4+CD25+FoxP3+ cells (Tregs). In the present study, we assessed the effect of haemodialysis (HD) on the Treg population. CD3+CD4+, CD3+CD8+ and CD4+CD25+FoxP3+ cells were estimated by flow cytometry in 142 ESRD patients (45 ESRD-preHD, 97 on HD) and 30 healthy controls (HC). Patients on HD were classified into three...
Paper Details
Title
End stage renal disease has an early and continuous detrimental effect on regulatory T cells
Published Date
Nov 15, 2021
Journal
Volume
27
Issue
3
Pages
281 - 287
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