Shining a light on autophagy in neurodegenerative diseases
Volume: 298, Issue: 1, Pages: 101437 - 101437
Published: Jan 1, 2022
Abstract
Small-molecule modulators of autophagy have been widely investigated as potential therapies for neurodegenerative diseases. In a recent issue of JBC, Safren et al. described a novel assay that uses a photoconvertible fusion protein to identify compounds that alter autophagic flux. Autophagy inducers identified using this assay were found to either alleviate or exacerbate neurotoxicity in different cellular models of amyotrophic lateral...
Paper Details
Title
Shining a light on autophagy in neurodegenerative diseases
Published Date
Jan 1, 2022
Volume
298
Issue
1
Pages
101437 - 101437
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