High throughput interrogation of human liver stellate cells reveals microenvironmental regulation of phenotype
Abstract
Liver fibrosis is a common feature of progressive liver disease and is manifested as a dynamic series of alterations in both the biochemical and biophysical properties of the liver. Hepatic stellate cells (HSCs) reside within the perisinusoidal space of the liver sinusoid and are one of the main drivers of liver fibrosis, yet it remains unclear how changes to the sinusoidal microenvironment impact HSC phenotype in the context of liver fibrosis....
Paper Details
Title
High throughput interrogation of human liver stellate cells reveals microenvironmental regulation of phenotype
Published Date
Jan 1, 2022
Journal
Volume
138
Pages
240 - 253
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Notes
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