Kinase Inhibition as Treatment for Acute and Chronic Graft-Versus-Host Disease
Abstract
Allogeneic hematopoietic stem cell transplantation (allo-HCT) is a potentially curative therapy for patients suffering from hematological malignancies via the donor immune system driven graft-versus-leukemia effect. However, the therapy is mainly limited by severe acute and chronic graft-versus-host disease (GvHD), both being life-threatening complications after allo-HCT. GvHD develops when donor T cells do not only recognize remaining tumor...
Paper Details
Title
Kinase Inhibition as Treatment for Acute and Chronic Graft-Versus-Host Disease
Published Date
Nov 17, 2021
Journal
Volume
12
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Notes
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