Tasquinimod efficacy and S100A9 expression in glucose-treated HREC cells

PURPOSE Diabetic retinopathy (DR) is one of the leading causes of blindness in working-aged people. Few studies were on the relationship between S100 Calcium Binding Protein A9 (S100A9) protein and DR, and none on endothelial cells induced by tasquinimod in high glucose. Therefore, we assessed the relationship between tasquinimod and S100A9 in DR. METHODS DR pathogenesis was simulated using high-glucose-induced human retinal endothelial cells...