Remodeling Macrophages by an Iron Nanotrap for Tumor Growth Suppression
Abstract
Tumor-associated macrophages (TAMs) that infiltrate in most tumor tissues are closely correlated with proliferation and metastasis of tumor cells. Immunomodulation of TAMs from pro-tumorigenic M2 phenotype to anti-tumorigenic M1 phenotype is crucial for oncotherapy. Herein, an iron nanotrap was utilized to remodel TAMs for tumor growth inhibition. In the formulation, the ultrasmall nanotrap could capture and targetedly transport endogenous iron...
Paper Details
Title
Remodeling Macrophages by an Iron Nanotrap for Tumor Growth Suppression
Published Date
Nov 16, 2021
Journal
Volume
15
Issue
12
Pages
19298 - 19309
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Notes
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