Claudins: Beyond Tight Junctions in Human IBD and Murine Models
Abstract
Claudins are transmembrane proteins constituting one of three tight junction protein families. In patients with inflammatory bowel disease (IBD), disease activity-dependent changes in expression of certain claudins have been noted, thus making certain claudin family members potential therapy targets. A study was undertaken with the aim of exploring expression of claudins in human disease and two different animal models of IBD: dextrane sulfate...
Paper Details
Title
Claudins: Beyond Tight Junctions in Human IBD and Murine Models
Published Date
Nov 17, 2021
Journal
Volume
12
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