A Randomized Trial of Radiotherapy vs. Trans-Oral Surgery for Treatment De-Escalation in HPV-Associated Oropharyngeal Squamous Cell Carcinoma (ORATOR2)

Volume: 111, Issue: 5, Pages: 1324 - 1325
Published: Dec 1, 2021
Abstract

Purpose/Objective(s)

Widespread oral human papillomavirus (HPV) infections have led to a rapid increase in the incidence of oropharyngeal squamous cell carcinoma (OPSCC). HPV-related OPSCCs have a better prognosis than conventional alcohol- and smoking-related OPSCCs, suggesting a role for treatment de-escalation. The goal of this phase II randomized trial was to assess survival, oncologic, and toxicity outcomes with two de-escalation...
Paper Details
Title
A Randomized Trial of Radiotherapy vs. Trans-Oral Surgery for Treatment De-Escalation in HPV-Associated Oropharyngeal Squamous Cell Carcinoma (ORATOR2)
Published Date
Dec 1, 2021
Volume
111
Issue
5
Pages
1324 - 1325
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