PKC-Delta-Dependent Pathways Contribute to the Exacerbation of the Platelet Activity in Crohn's Disease

The pathogenesis of inflammatory bowel diseases (IBD), representing chronic and relapsing-remitting disorders of the gastrointestinal tract, encompasses Crohn's disease (CD) and ulcerative colitis.[1] [2] Although the cause and mechanisms of both conditions remain unknown, mounting evidence suggests that gut tissue injury is not exclusively the result of a dysregulated immune response, but also involves the active participation of multiple...