Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions
Abstract
Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions. Whether chronic overlapping pain conditions represent a distinct pathophysiology from the occurrence of pain at only one site is unknown. Using genome-wide approaches, we compared genetic determinants of chronic single-site versus multisite pain in the UK Biobank. We found that different genetic signals underlie chronic single-site...
Paper Details
Title
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions
Published Date
Nov 11, 2021
Journal
Volume
145
Issue
3
Pages
1111 - 1123
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