Strong evidence for parasympathetic sinoatrial reinnervation after heart transplantation

Heart transplantation (HTx) surgically denervates the heart. We examined indices of sinoatrial reinnervation, with emphasis on (1) the occurrence and timing of parasympathetic reinnervation, and (2) the consequences of reinnervation for heart rate (HR) responsiveness and arterial baroreceptor sensitivity.Fifty HTx recipients were prospectively followed for 36 months after surgery. Hemodynamic variables and heart rate variability were...