Dual methylation and hydroxymethylation study of alcohol use disorder
Abstract
Using an integrative, multi-tissue design, we sought to characterize methylation and hydroxymethylation changes in blood and brain associated with alcohol use disorder (AUD). First, we used epigenomic deconvolution to perform cell-type-specific methylome-wide association studies within subpopulations of granulocytes/T-cells/B-cells/monocytes in 1132 blood samples. Blood findings were then examined for overlap with AUD-related associations with...
Paper Details
Title
Dual methylation and hydroxymethylation study of alcohol use disorder
Published Date
Nov 17, 2021
Journal
Volume
27
Issue
2
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