Long non‑coding RNA MIR17HG sponges microRNA‑21 to upregulate PTEN and regulate homoharringtonine‑based chemoresistance of acute myeloid leukemia cells
Abstract
Long non-coding (lnc)RNA MIR17HG has been identified as a oncogene whose roles in acute myeloid leukemia (AML) remain unclear. The present study aimed to investigate the role of lncRNA MIR17HG in AML. Differential expression of MIR17HG in AML was determined by reverse transcription-quantitative PCR. Overexpression assays and dual luciferase reporter assays were performed to determine the relationship between MIR17HG and microRNA (miR)-21, and...
Paper Details
Title
Long non‑coding RNA MIR17HG sponges microRNA‑21 to upregulate PTEN and regulate homoharringtonine‑based chemoresistance of acute myeloid leukemia cells
Published Date
Nov 18, 2021
Journal
Volume
23
Issue
1
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